ML-Flex: A Flexible Toolbox for Performing Classification Analyses In Parallel

Stephen R. Piccolo, Lewis J. Frey.

Year: 2012, Volume: 13, Issue: 19, Pages: 555−559


Motivated by a need to classify high-dimensional, heterogeneous data from the bioinformatics domain, we developed ML-Flex, a machine-learning toolbox that enables users to perform two-class and multi-class classification analyses in a systematic yet flexible manner. ML-Flex was written in Java but is capable of interfacing with third-party packages written in other programming languages. It can handle multiple input-data formats and supports a variety of customizations. ML-Flex provides implementations of various validation strategies, which can be executed in parallel across multiple computing cores, processors, and nodes. Additionally, ML-Flex supports aggregating evidence across multiple algorithms and data sets via ensemble learning. This open-source software package is freely available from

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